POLY(ETHYLENE GLYCOL) - NANOSILICATE SACRIFICIAL INK FOR CERAMIC MATERIAL EXTRUSION ADDITIVE MANUFACTURING
"2022-02-21" // app/Providers/../Base/Publico/Artigo/resources/show_includes/info_artigo.blade.php
App\Base\Administrativo\Model\Artigo {#1843 // app/Providers/../Base/Publico/Artigo/resources/show_includes/info_artigo.blade.php #connection: "mysql" +table: "artigo" #primaryKey: "id" #keyType: "int" +incrementing: true #with: [] #withCount: [] +preventsLazyLoading: false #perPage: 15 +exists: true +wasRecentlyCreated: false #escapeWhenCastingToString: false #attributes: array:35 [ "id" => 83317 "edicao_id" => 195 "trabalho_id" => 29 "inscrito_id" => 51 "titulo" => "POLY(ETHYLENE GLYCOL) - NANOSILICATE SACRIFICIAL INK FOR CERAMIC MATERIAL EXTRUSION ADDITIVE MANUFACTURING" "resumo" => "THERE ARE MANY TECHNIQUES TO PRODUCE CERAMIC AND BIOGLASS SCAFFOLDS, EACH ONE WITH ADVANTAGES AND LIMITATIONS. AMONG THEM, ADDITIVE MANUFACTURING (AM), FOAM REPLICA AND FREEZE-DRYING ARE WIDELY USED. DESPITE PREVIOUS WORKS INVESTIGATING THE FABRICATION OF BIOCERAMIC SCAFFOLDS, SOME GAPS STILL NEED TO BE FULFILLED TO ESTABLISH COST-EFFECTIVITY ROUTES WITH SATISFACTORY REPRODUCIBILITY AND ACCURACY [1–3]. AS AN ALTERNATIVE, THE USE OF AM TECHNIQUES TO CONSTRUCT THREE-DIMENSIONAL (3D) STRUCTURES HAS BEEN WIDELY EXPLORED, CONSIDERING THE FABRICATION OF COMPLEX STRUCTURES AS THE MAIN ADVANTAGE. HOWEVER, THE MASSIVE SEARCH FOR INK FORMULATIONS THAT ARE EASY TO OBTAIN, LOW COST AND SUITABLE FOR AM TECHNOLOGIES REMAINS A CHALLENGE [4,5]. SACRIFICIAL INKS FROM BIOMATERIALS CAN BE 3D PRINTED, RESULTING IN BIOCOMPATIBLE 3D STRUCTURES THAT CAN BE LEACHED OR DISSOLVED AFTER FULFILLING THEIR FUNCTION WITHOUT CHANGING THE MEDIUM AFTER THEIR DEGRADATION [6]. THESE MATERIALS ARE COMMONLY TRANSFORMED IN GEL OR LIQUID UNDER MECHANICAL, PHYSICAL OR CHEMICAL STIMULI. ITS APPLICATION HAS BEEN USED BASICALLY IN TWO WAYS: IN CREATING FREE SPACES WITHIN 3D STRUCTURES OF COMPLEX GEOMETRY, AS THE CREATION OF INTERNAL CHANNELS (FUGITIVE), OR AS SUPPORT MATERIALS [7]. IN THIS WAY, POLY(ETHYLENE GLYCOL) (PEG) HYDROGELS ARISE AS AN INTERESTING ALTERNATIVE FOR SACRIFICIAL INK FORMULATION TO DESIGN CERAMIC SCAFFOLDS, BASED ON THEIR SHEAR-THINNING BEHAVIOR, WHICH IS ESSENTIAL FOR MATERIAL AM. IN THIS STUDY, SACRIFICIAL INKS BASED ON PEG-400 AND LAPONITE NANOSILICATE WERE OBTAINED AND CHARACTERIZED. INITIALLY, THE RHEOLOGICAL PROPERTIES OF DIFFERENT LAPONITE CONCENTRATIONS (5, 7.5, AND 10% W/W) WERE EVALUATED TO ESTABLISH THEIR INFLUENCE OVER THE PEG VISCOSITY PROFILE. AS A RESULT, THE VISCOSITY OF THE PEG-400 SOLUTION INCREASED DRAMATICALLY AS A FUNCTION OF THE ADDITION OF LAPONITE, CHARACTERIZING A STRONG SHEAR-THINNING AND SOLID-LIKE RHEOLOGICAL BEHAVIOR, IDEAL FOR MATERIAL EXTRUSION AM. ALSO, THE SHAPE OF THE INK AT THE NOZZLE TIP WAS OBSERVED TO VERIFY THE EXTRUSION OF FILAMENTS. THEN, MULTI-LAYER PENTAGRAM TUBE-LIKE STRUCTURES WERE DESIGNED FOR PRINTABILITY EVALUATION. THE MORPHOLOGICAL FEATURE OF THESE STRUCTURES WAS INVESTIGATED AND IMAGED WITH A STEREOMICROSCOPE; AS OBSERVED, TAILORED RHEOLOGICAL PROPERTIES ENABLED THE MATERIAL DEPOSITION OF THESE MULTI-LAYER SAMPLES, WHICH COULD RETAIN THEIR SHAPE IN THE CONSTRUCTION PLATFORM. THE LATTER ALLOWED THE DEVELOPMENT OF BIOSILICATE® (BIOS) SCAFFOLDS COMPRISING 70% (V/V) OF CERAMIC FILLER. THE GREEN SAMPLES SHOWED GOOD REPRODUCIBILITY IN THE DEPOSITION OF THE EXTRUDED FILAMENTS AND THE ADHESION POINTS BETWEEN THE LAYERS. THEY DO NOT PRESENT DEFECTS AND PORES AFTER THE SINTERING POST-PROCESSING STEP. FINALLY, THE CHEMICAL COMPOSITION WAS ANALYZED BY FTIR AND THE THERMAL STABILITY BY TGA; AS OBSERVED, THE SACRIFICIAL INK WAS REMOVED THROUGH HEAT TREATMENT, WHICH DOES NOT COMPROMISE THE STRUCTURE NOR CHANGE THE FINAL COMPOSITION OF THE ORIGINAL CERAMIC MATERIAL. IN CONCLUSION, BEARING IN MIND THE INCREASING DEMAND FOR INKS WITH EXCELLENT PRINTABILITY TO GENERATE SHAPE FIDELITY, THE FORMULATED PEG-LAPONITE INK PRESENTS RHEOLOGICAL PROPERTIES THAT MAKE IT PROMISING FOR EXTRUSION-BASED 3D PRINTING OF BIOS SCAFFOLDS, WHERE THE MAIN TARGET ARE BONE TISSUE REGENERATION APPLICATIONS." "modalidade" => "Oral form" "area_tematica" => "NEW MATERIALS FOR BIOLOGICAL APPLICATIONS" "palavra_chave" => "ADDITIVE MANUFACTURING, BIOSILICATE, NANOSILICATE LAPONITE, POLY(ETHYLENE GLYCOL), SACRIFICIAL INK" "idioma" => "Português" "arquivo" => "TRABALHO_EV170_MD1_SA101_ID51_19112021162709.pdf" "created_at" => "2022-02-16 10:17:52" "updated_at" => null "ativo" => 1 "autor_nome" => "KARINA FELICIANO SANTOS" "autor_nome_curto" => "KARINAFS30" "autor_email" => "karinafs30@hotmail.com" "autor_ies" => "UNIVERSIDADE FEDERAL DO ABC" "autor_imagem" => "" "edicao_url" => "anais-do-latin-american-congress-of-artificial-organs-and-biomaterials" "edicao_nome" => "Anais do XI Latin American Congress of Artificial Organs and Biomaterials (COLAOB)" "edicao_evento" => "XI Latin American Congress of Artificial Organs and Biomaterials" "edicao_ano" => 2022 "edicao_pasta" => "anais/colaob/2021" "edicao_logo" => null "edicao_capa" => "61fc15636d9b1_03022022144819.jpg" "data_publicacao" => "2022-02-21" "edicao_publicada_em" => "2022-01-26 10:43:13" "publicacao_id" => 91 "publicacao_nome" => "Revista do Latin American Congresso of Artificial Organs and Biomaterials (COLAOB)" "publicacao_codigo" => "978-65-86901-54-2" "tipo_codigo_id" => 2 "tipo_codigo_nome" => "ISBN" "tipo_publicacao_id" => 1 "tipo_publicacao_nome" => "ANAIS de Evento" ] #original: array:35 [ "id" => 83317 "edicao_id" => 195 "trabalho_id" => 29 "inscrito_id" => 51 "titulo" => "POLY(ETHYLENE GLYCOL) - NANOSILICATE SACRIFICIAL INK FOR CERAMIC MATERIAL EXTRUSION ADDITIVE MANUFACTURING" "resumo" => "THERE ARE MANY TECHNIQUES TO PRODUCE CERAMIC AND BIOGLASS SCAFFOLDS, EACH ONE WITH ADVANTAGES AND LIMITATIONS. AMONG THEM, ADDITIVE MANUFACTURING (AM), FOAM REPLICA AND FREEZE-DRYING ARE WIDELY USED. DESPITE PREVIOUS WORKS INVESTIGATING THE FABRICATION OF BIOCERAMIC SCAFFOLDS, SOME GAPS STILL NEED TO BE FULFILLED TO ESTABLISH COST-EFFECTIVITY ROUTES WITH SATISFACTORY REPRODUCIBILITY AND ACCURACY [1–3]. AS AN ALTERNATIVE, THE USE OF AM TECHNIQUES TO CONSTRUCT THREE-DIMENSIONAL (3D) STRUCTURES HAS BEEN WIDELY EXPLORED, CONSIDERING THE FABRICATION OF COMPLEX STRUCTURES AS THE MAIN ADVANTAGE. HOWEVER, THE MASSIVE SEARCH FOR INK FORMULATIONS THAT ARE EASY TO OBTAIN, LOW COST AND SUITABLE FOR AM TECHNOLOGIES REMAINS A CHALLENGE [4,5]. SACRIFICIAL INKS FROM BIOMATERIALS CAN BE 3D PRINTED, RESULTING IN BIOCOMPATIBLE 3D STRUCTURES THAT CAN BE LEACHED OR DISSOLVED AFTER FULFILLING THEIR FUNCTION WITHOUT CHANGING THE MEDIUM AFTER THEIR DEGRADATION [6]. THESE MATERIALS ARE COMMONLY TRANSFORMED IN GEL OR LIQUID UNDER MECHANICAL, PHYSICAL OR CHEMICAL STIMULI. ITS APPLICATION HAS BEEN USED BASICALLY IN TWO WAYS: IN CREATING FREE SPACES WITHIN 3D STRUCTURES OF COMPLEX GEOMETRY, AS THE CREATION OF INTERNAL CHANNELS (FUGITIVE), OR AS SUPPORT MATERIALS [7]. IN THIS WAY, POLY(ETHYLENE GLYCOL) (PEG) HYDROGELS ARISE AS AN INTERESTING ALTERNATIVE FOR SACRIFICIAL INK FORMULATION TO DESIGN CERAMIC SCAFFOLDS, BASED ON THEIR SHEAR-THINNING BEHAVIOR, WHICH IS ESSENTIAL FOR MATERIAL AM. IN THIS STUDY, SACRIFICIAL INKS BASED ON PEG-400 AND LAPONITE NANOSILICATE WERE OBTAINED AND CHARACTERIZED. INITIALLY, THE RHEOLOGICAL PROPERTIES OF DIFFERENT LAPONITE CONCENTRATIONS (5, 7.5, AND 10% W/W) WERE EVALUATED TO ESTABLISH THEIR INFLUENCE OVER THE PEG VISCOSITY PROFILE. AS A RESULT, THE VISCOSITY OF THE PEG-400 SOLUTION INCREASED DRAMATICALLY AS A FUNCTION OF THE ADDITION OF LAPONITE, CHARACTERIZING A STRONG SHEAR-THINNING AND SOLID-LIKE RHEOLOGICAL BEHAVIOR, IDEAL FOR MATERIAL EXTRUSION AM. ALSO, THE SHAPE OF THE INK AT THE NOZZLE TIP WAS OBSERVED TO VERIFY THE EXTRUSION OF FILAMENTS. THEN, MULTI-LAYER PENTAGRAM TUBE-LIKE STRUCTURES WERE DESIGNED FOR PRINTABILITY EVALUATION. THE MORPHOLOGICAL FEATURE OF THESE STRUCTURES WAS INVESTIGATED AND IMAGED WITH A STEREOMICROSCOPE; AS OBSERVED, TAILORED RHEOLOGICAL PROPERTIES ENABLED THE MATERIAL DEPOSITION OF THESE MULTI-LAYER SAMPLES, WHICH COULD RETAIN THEIR SHAPE IN THE CONSTRUCTION PLATFORM. THE LATTER ALLOWED THE DEVELOPMENT OF BIOSILICATE® (BIOS) SCAFFOLDS COMPRISING 70% (V/V) OF CERAMIC FILLER. THE GREEN SAMPLES SHOWED GOOD REPRODUCIBILITY IN THE DEPOSITION OF THE EXTRUDED FILAMENTS AND THE ADHESION POINTS BETWEEN THE LAYERS. THEY DO NOT PRESENT DEFECTS AND PORES AFTER THE SINTERING POST-PROCESSING STEP. FINALLY, THE CHEMICAL COMPOSITION WAS ANALYZED BY FTIR AND THE THERMAL STABILITY BY TGA; AS OBSERVED, THE SACRIFICIAL INK WAS REMOVED THROUGH HEAT TREATMENT, WHICH DOES NOT COMPROMISE THE STRUCTURE NOR CHANGE THE FINAL COMPOSITION OF THE ORIGINAL CERAMIC MATERIAL. IN CONCLUSION, BEARING IN MIND THE INCREASING DEMAND FOR INKS WITH EXCELLENT PRINTABILITY TO GENERATE SHAPE FIDELITY, THE FORMULATED PEG-LAPONITE INK PRESENTS RHEOLOGICAL PROPERTIES THAT MAKE IT PROMISING FOR EXTRUSION-BASED 3D PRINTING OF BIOS SCAFFOLDS, WHERE THE MAIN TARGET ARE BONE TISSUE REGENERATION APPLICATIONS." "modalidade" => "Oral form" "area_tematica" => "NEW MATERIALS FOR BIOLOGICAL APPLICATIONS" "palavra_chave" => "ADDITIVE MANUFACTURING, BIOSILICATE, NANOSILICATE LAPONITE, POLY(ETHYLENE GLYCOL), SACRIFICIAL INK" "idioma" => "Português" "arquivo" => "TRABALHO_EV170_MD1_SA101_ID51_19112021162709.pdf" "created_at" => "2022-02-16 10:17:52" "updated_at" => null "ativo" => 1 "autor_nome" => "KARINA FELICIANO SANTOS" "autor_nome_curto" => "KARINAFS30" "autor_email" => "karinafs30@hotmail.com" "autor_ies" => "UNIVERSIDADE FEDERAL DO ABC" "autor_imagem" => "" "edicao_url" => "anais-do-latin-american-congress-of-artificial-organs-and-biomaterials" "edicao_nome" => "Anais do XI Latin American Congress of Artificial Organs and Biomaterials (COLAOB)" "edicao_evento" => "XI Latin American Congress of Artificial Organs and Biomaterials" "edicao_ano" => 2022 "edicao_pasta" => "anais/colaob/2021" "edicao_logo" => null "edicao_capa" => "61fc15636d9b1_03022022144819.jpg" "data_publicacao" => "2022-02-21" "edicao_publicada_em" => "2022-01-26 10:43:13" "publicacao_id" => 91 "publicacao_nome" => "Revista do Latin American Congresso of Artificial Organs and Biomaterials (COLAOB)" "publicacao_codigo" => "978-65-86901-54-2" "tipo_codigo_id" => 2 "tipo_codigo_nome" => "ISBN" "tipo_publicacao_id" => 1 "tipo_publicacao_nome" => "ANAIS de Evento" ] #changes: [] #casts: array:14 [ "id" => "integer" "edicao_id" => "integer" "trabalho_id" => "integer" "inscrito_id" => "integer" "titulo" => "string" "resumo" => "string" "modalidade" => "string" "area_tematica" => "string" "palavra_chave" => "string" "idioma" => "string" "arquivo" => "string" "created_at" => "datetime" "updated_at" => "datetime" "ativo" => "boolean" ] #classCastCache: [] #attributeCastCache: [] #dates: [] #dateFormat: null #appends: [] #dispatchesEvents: [] #observables: [] #relations: [] #touches: [] +timestamps: false #hidden: [] #visible: [] +fillable: array:13 [ 0 => "edicao_id" 1 => "trabalho_id" 2 => "inscrito_id" 3 => "titulo" 4 => "resumo" 5 => "modalidade" 6 => "area_tematica" 7 => "palavra_chave" 8 => "idioma" 9 => "arquivo" 10 => "created_at" 11 => "updated_at" 12 => "ativo" ] #guarded: array:1 [ 0 => "*" ] }